Description

Functions​

• Mucolytic agent: NAC specifically targets respiratory mucus, breaking disulfide bonds in mucoproteins through its sulfhydryl group. This action reduces mucus viscosity, making it easier to expel and alleviating symptoms of respiratory diseases like chronic obstructive pulmonary disease (COPD) and bronchitis.​
• Antioxidant: As a powerful antioxidant, NAC scavenges free radicals such as superoxide anions and hydroxyl radicals. Additionally, it serves as a precursor for glutathione (GSH) synthesis, enhancing cellular antioxidant defenses and protecting against oxidative stress, which is vital for anti-aging and preventing chronic diseases.​
• Detoxification: Clinically, NAC is the antidote for acetaminophen (paracetamol) overdose. It conjugates with toxic metabolites of acetaminophen, promoting their elimination and reducing the risk of liver failure.​

Applications​

• Medical: Besides treating respiratory conditions and drug poisoning, NAC aids in managing liver diseases like viral hepatitis and alcoholic liver disease. Its antioxidant and anti-inflammatory properties also spark research interest in treating neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases.​
• Dietary supplements: Widely added to health products, NAC caters to consumers seeking antioxidant benefits and immune enhancement, especially for those exposed to environmental pollution, under stress, or with smoking habits.​
• Cosmetics: In skincare, NAC’s antioxidant and cell-repair functions reduce oxidative damage from UV radiation and pollution. It helps with anti-wrinkle, skin-whitening, and repairing the skin barrier, commonly included in serums and masks.