Description

Function

1. Antioxidant Properties:
   • ALA is a powerful antioxidant that can neutralize reactive oxygen species (ROS) and regenerate other antioxidants like vitamin C and E。It also helps increase cellular levels of glutathione, earning it the nickname “the antioxidant of antioxidants”.
2. Glucose Metabolism:
   • ALA improves insulin sensitivity and glucose uptake in both insulin-sensitive and insulin-resistant tissues。It activates AMP-activated protein kinase (AMPK), which enhances glucose uptake and fatty acid oxidation.
3. Neuroprotection:
   • ALA has been shown to protect nerve tissue from oxidative damage and improve symptoms of diabetic peripheral neuropathy。It is used as a racemic drug for treating diabetic polyneuropathy-associated pain and paresthesia.
4. Cardiovascular Health:
   • ALA supports cardiovascular health by reducing oxidative stress, improving endothelial function, and inhibiting the formation of atherosclerotic plaques.
5. Detoxification:
   • ALA can chelate heavy metals, reducing their toxicity and supporting the body’s natural detoxification processes.
6. Anti-inflammatory Effects:
   • ALA modulates various signaling pathways, including NF-κB, reducing inflammation and supporting overall health.

Application

1. Supplements:
   • ALA is available as a dietary supplement to support antioxidant activity, glucose metabolism, and overall health.
2. Medical Uses:
   • ALA is used in the treatment of diabetic neuropathy, improving symptoms such as pain and numbness。It is also studied for its potential benefits in conditions like obesity, metabolic syndrome, and cardiovascular diseases.
3. Cosmetics:
   • Due to its antioxidant properties, ALA is used in skincare products to protect the skin from oxidative damage and reduce signs of aging.
4. Research:
   • ALA is being investigated for its potential use in cancer therapy, where it has shown promise in inhibiting cancer cell proliferation and promoting apoptosis.