Bis(glycinato)manganese

Bis(glycinato)manganese

Bis(glycinato)manganese, also known as manganese glycinate chelate, is a coordination compound formed by the bonding of manganese ions with two glycine molecules. It typically presents as a light pink to brownish powder, which showcases good solubility in water. The chelation process significantly enhances the stability of manganese within the compound. This not only improves the bioavailability of manganese, making it more readily absorbed by the body, but also reduces the potential for causing gastrointestinal irritation, which is often associated with inorganic forms of manganese. Structurally, the glycine molecules act as ligands, surrounding the manganese ion and creating a complex that is both chemically stable and biologically accessible.

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Description

Product Name Bis(glycinato)manganese
Appearance White Powder
Specification Manganese 15% 20%
Test Method HPLC
CAS No 14281-77-7
MF C4H6MnN2O4
Certificate KOSHER/HALAL/ISO/CGMP/USDAORGANIC

Functions​

  • Enzyme Activation: Manganese in this compound acts as a cofactor for over 300 enzymes. Notably, it activates superoxide dismutase (SOD), a key antioxidant enzyme that neutralizes harmful free radicals, protecting cells from oxidative stress linked to aging and diseases. It also participates in carbohydrate metabolism by activating enzymes involved in glycolysis and gluconeogenesis, maintaining energy homeostasis.​
  • Bone Health: Crucial for bone development, bis(glycinato)manganese aids in the synthesis of proteoglycans, essential components of bone and cartilage extracellular matrix. By promoting the deposition of calcium and other minerals, it contributes to bone density and strength, reducing the risk of osteoporosis.​
  • Wound Healing Support: It plays a role in wound healing by enhancing collagen synthesis, a vital protein for tissue repair. Additionally, it activates immune cells at the wound site, helping prevent infection and accelerate the healing process.​

Applications​

  • Dietary Supplements: Commonly included in multinutrient formulations, it targets individuals at risk of manganese deficiency, such as vegetarians and those with digestive disorders. Its enhanced bioavailability ensures efficient absorption, making it a preferred choice for maintaining overall health, cognitive function, and bone integrity.​
  • Animal Feed: Added to livestock feed, it improves the growth and reproductive health of animals. In poultry, it aids in eggshell formation and chick development, while in swine, it supports muscle growth and meat quality, enhancing overall productivity in the agricultural industry.