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Calcium D-Glucarate is the calcium salt of D-glucaric acid, derived from glucose oxidation. Appearing as a white crystalline powder, it is highly soluble in water, making it suitable for various applications in dietary supplements, food additives, and pharmaceutical excipients. Its unique chemical properties enable it to contribute to both detoxification processes and calcium supply in the body.
Product Name | Calcium D-Glucarate |
Appearance | White powder |
Specification | 99% |
Test Method | HPLC |
CAS No | 299-28-5 |
MF | C12H22CaO14 |
Certificate | KOSHER/HALAL/ISO/CGMP/USDAORGANIC |
Functions
Detoxification: Calcium D-Glucarate inhibits β-glucuronidase, an enzyme that can reactivate certain toxins and hormones that the body has already conjugated for elimination. By inhibiting this enzyme, it recycles glucuronic acid for phase II metabolism, enhancing the body’s ability to eliminate toxins, including carcinogens, environmental pollutants, and excess hormones. Studies have shown that supplementation with Calcium D-Glucarate can increase the excretion of these harmful substances, supporting liver detoxification and reducing the body’s toxic burden.
Calcium Supply: As a source of calcium, it plays a vital role in maintaining bone health. Calcium is essential for bone density, strength, and remodeling. Adequate calcium intake, especially during childhood, adolescence, and in postmenopausal women, helps prevent osteoporosis and reduces the risk of fractures. Calcium D-Glucarate also supports muscle function, as calcium ions are involved in muscle contraction and relaxation. Additionally, it is important for nerve transmission, enabling proper communication between nerve cells.
Antioxidant and Anti-inflammatory: Calcium D-Glucarate exhibits antioxidant and anti-inflammatory effects. It helps protect cells from oxidative damage caused by free radicals, reducing the risk of chronic diseases. Inflammation is linked to many health issues, and by modulating inflammatory pathways, Calcium D-Glucarate may help alleviate symptoms of inflammatory conditions such as arthritis and inflammatory bowel disease. It supports overall cellular health and well-being by reducing oxidative stress and inflammation.
Applications
Detox Supplements: Widely used in liver detox products, Calcium D-Glucarate is often included in cleansing formulas aimed at supporting the body’s natural detoxification processes. These supplements are popular among individuals looking to improve their overall health, reduce exposure to toxins, or support liver function after periods of high toxin exposure, such as during or after a course of medication. It’s also found in weight management supplements, as detoxification is sometimes associated with improved metabolism and weight loss.
Food Fortification: Added to various foods and beverages, Calcium D-Glucarate serves as a calcium fortifier. It’s commonly found in juices, cereals, and dairy alternatives, providing consumers with an easy way to increase their calcium intake. Fortified foods are especially important for individuals with dietary restrictions or those who may not consume enough calcium-rich foods, such as vegetarians or individuals with lactose intolerance.
Pharmaceutical Excipients: In the pharmaceutical industry, Calcium D-Glucarate is used as a buffering agent in tablet formulations. It helps maintain the stability and pH of the tablet, ensuring the effectiveness of the active ingredients. Its solubility and chemical properties make it a useful excipient for various drug delivery systems, contributing to the quality and performance of pharmaceutical products.